תזונה ותוספים Longer Breastfeeding Is Associated with Increased Lower Body Explosive Strength durin

[Mike Bikov]

J Nutr. 2010 Sep 22. [Epub ahead of print]
Longer Breastfeeding Is Associated with Increased Lower Body Explosive Strength during Adolescence.

Artero EG, Ortega FB, España-Romero V, Labayen I, Huybrechts I, Papadaki A, Rodriguez G, Mauro B, Widhalm K, Kersting M, Manios Y, Molnar D, Moreno LA, Sjöström M, Gottrand F, Castillo MJ, De Henauw S.

EFFECTS-262 Research Group, Department of Physiology, School of Medicine, University of Granada, Granada SP-18012, Spain.
Abstract

Our aim in this study was to examine the association between breastfeeding duration and cardiorespiratory fitness, isometric strength, and explosive strength during adolescence. A total of 2567 adolescents (1426 girls) from the Healthy Lifestyle in Europe by Nutrition in Adolescence (HELENA) cross-sectional study aged 12.5-17.5 y were included. Information about duration of any and exclusive breastfeeding was obtained retrospectively by means of a parental questionnaire. The 20-m shuttle run, handgrip strength, and standing long jump tests were used to assess physical fitness. Significant differences among the categories of breastfeeding duration were tested using ANCOVA after adjusting for a set of potential confounders: gestational and current age, birth weight, sexual maturation, fat mass, fat-free mass, maternal education, parental weight status, country, smoking behavior, and days of vigorous physical activity. Longer breastfeeding (either any or exclusive) was associated with a higher performance in the standing long jump test in both boys and girls (P < 0.001), regardless of fat mass, fat-free mass, and the rest of potential confounders. In adolescents who were breastfed for 3-5 mo or ≥6 mo, the risk of having a standing long jump performance below the 5th percentile was reduced by half compared with those who were never breastfed [odds ratio (OR) = 0.54, 95% CI = 0.30-0.96, P < 0.05; and OR = 0.40, 95% CI = 0.22-0.74, P < 0.01, respectively). These findings suggest a role of breastfeeding in determining lower body explosive strength during adolescence.

PMID: 20861216 [PubMed - as supplied by publisher]​

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[EMZ]

מי מביא את הרעיונות האלה למחקר? אלוהים.

 

[Mike Bikov]

אתה לא רוצה לדעת מה אני קורא ולא מפרסם, היום היה מחקר של AMPK אצל זבובים בדרום אפריקה.

 

[EMZ]

דרוזופילה?!?!

 

[Mike Bikov]

PLoS One. 2010 Sep 20;5(9). pii: e12799.
Altered Metabolism and Persistent Starvation Behaviors Caused by Reduced AMPK Function in Drosophila.
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Johnson EC, Kazgan N, Bretz CA, Forsberg LJ, Hector CE, Worthen RJ, Onyenwoke R, Brenman JE.
Department of Biology, Wake Forest University, Winston-Salem, North Carolina, United States of America.
Abstract
​

Organisms must utilize multiple mechanisms to maintain energetic homeostasis in the face of limited nutrient availability. One mechanism involves activation of the heterotrimeric AMP-activated protein kinase (AMPK), a cell-autonomous sensor to energetic changes regulated by ATP to AMP ratios. We examined the phenotypic consequences of reduced AMPK function, both through RNAi knockdown of the gamma subunit (AMPKγ) and through expression of a dominant negative alpha (AMPKα) variant in Drosophila melanogaster. Reduced AMPK signaling leads to hypersensitivity to starvation conditions as measured by lifespan and locomotor activity. Locomotor levels in flies with reduced AMPK function were lower during unstressed conditions, but starvation-induced hyperactivity, an adaptive response to encourage foraging, was significantly higher than in wild type. Unexpectedly, total dietary intake was greater in animals with reduced AMPK function yet total triglyceride levels were lower. AMPK mutant animals displayed starvation-like lipid accumulation patterns in metabolically key liver-like cells, oenocytes, even under fed conditions, consistent with a persistent starved state. Measurements of O(2) consumption reveal that metabolic rates are greater in animals with reduced AMPK function. Lastly, rapamycin treatment tempers the starvation sensitivity and lethality associated with reduced AMPK function. Collectively, these results are consistent with models that AMPK shifts energy usage away from expenditures into a conservation mode during nutrient-limited conditions at a cellular level. The highly conserved AMPK subunits throughout the Metazoa, suggest such findings may provide significant insight for pharmaceutical strategies to manipulate AMPK function in humans.
PMID: 20862213 [PubMed - in process]​

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[EMZ]

בפאב מד יש יותר ספאם מהפורום 😃