תזונה ותוספים Effects of 8 weeks of Xpand® 2X pre workout supplementation on skeletal muscle hypertrophy, lean bod

[Mike Bikov]

Effects of 8 weeks of Xpand® 2X pre workout supplementation on skeletal muscle hypertrophy, lean body mass, and strength in resistance trained males

Ryan P Lowery1, Jordan M Joy1, Joshua E Dudeck1, Eduardo Oliveira de Souza2, Sean A McCleary1, Shawn Wells3, Robert Wildman3 and Jacob M Wilson1*


Author Affiliations
1 Department of Health Sciences and Human Performance, The University of Tampa, Tampa, FL, USA

2 Laboratory of Neuromuscular Adaptations to Strength Training, School of Physical Education and Sport, University of São Paulo, São Paulo, Brazil

3 Dymatize® Enterprises, LLC. & Dymatize® Nutrition Sport Performance Institute (DNSPI), Dallas, Texas, USA

Journal of the International Society of Sports Nutrition 2013, 10:44 doi:10.1186/1550-2783-10-44


Received: 19 June 2013
Accepted: 2 October 2013
Published: 9 October 2013

Abstract
Background
Xpand® 2X is a proprietary blend comprised of branched chain amino acids, creatine monohydrate, beta-alanine (CarnoSyn®), quercetin, coenzymated B-vitamins, alanyl-glutamine (Sustamine®), and natural nitrate sources from pomegranate and beet root extracts purported to enhance the neuromuscular adaptations of resistance training. However to date, no long-term studies have been conducted with this supplement. The purpose of this study was to investigate the effects of a multi-ingredient performance supplement (MIPS) on skeletal muscle hypertrophy, lean body mass and lower body strength in resistance-trained males.

Methods
Twenty resistance-trained males (21.3 ± 1.9 years) were randomly assigned to consume a MIPS or a placebo of equal weight and volume (food-grade orange flavors and sweeteners) in a double-blind manner, 30 minutes prior to exercise. All subjects participated in an 8-week, 3-day per week, periodized, resistance-training program that was split-focused on multi-joint movements such as leg press, bench press, and bent-over rows. Ultrasonography measured muscle thickness of the quadriceps, dual-energy X-ray absorptiometry (DEXA) determined lean body mass, and strength of the bench press and leg press were determined at weeks 0, 4, and 8 of the study. Data were analyzed with a 2 × 3 repeated measures ANOVA with LSD post hoc tests utilized to locate differences.

Results
There was a significant group-by-time interaction in which the MIPS supplementation resulted in a significant (p < 0.01) increase in strength of the bench press (18.4% vs. 9.6%) compared with placebo after 4 and 8 weeks of training. There were no significant group by time interactions between MIPS supplementation nor the placebo in leg press strength (p = .08). MIPS supplementation also resulted in a significant increase in lean body mass (7.8% vs. 3.6%) and quadriceps muscle thickness (11.8% vs. 4.5%) compared with placebo (group*time, p <0.01).

Conclusions
These results suggest that this MIPS can positively augment adaptations in strength, and skeletal muscle hypertrophy in resistance-trained men.​

המלא:
http://www.jissn.com/content/pdf/1550-2783-10-44.pdf

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לקחת בערבון מוגבל

מחקר מצחיק. התוסף מכיל, בין השאר, קריאטין שהשפעתו הטובה ידועה. הבדיקה נערכה כנגד פלסבו, לא כנגד קריאטין טהור. זה כמו שאני אייצר תוסף בשם "המעורר-סופר-דופר-בלי-השוואה-בכלל" שיכיל הרבה קפאין ואראה במחקר שהוא ממריץ יותר מפלסבו.