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:😃(Sports Med Arthrosc. 2011 Sep;19(3):218-26.
Role of growth factors in rotator cuff healing.
Oliva F, Via AG, Maffulli N.
Source
*Department of Orthopaedics and Traumatology, University of Rome "Tor Vergata" School of Medicine, Rome, Italy †Centre for Sports and Exercise Medicine Queen Mary University of London, Barts ‡The London School of Medicine and Dentistry, Mile End Hospital, London E1 4DG, UK.
Abstract
The histologic lesion underlying overuse rotator cuff tendinopathy is a failed healing response, with haphazard proliferation of tenocytes, disruption of tendon cells and collagen fibers, and increased noncollagenous extracellular matrix. Recent attention has focused on the biological pathways by which tendons heal, leading to the identification of several growth factors (GFs) involved in this process. No studies have been published on the time course of the various GFs during rotator cuff healing process in vivo, in humans. We review what is known about these GFs and their role in rotator cuff healing.
PMID:
21822105
[PubMed - in process]