תזונה ותוספים Markers of cardiovascular risk are not changed by increased whole-grain intake: the W

[Mike Bikov]

Br J Nutr. 2010 Mar 23:1-10. [Epub ahead of print]
Markers of cardiovascular risk are not changed by increased whole-grain intake: the WHOLEheart study, a randomised, controlled dietary intervention.

Brownlee IA, Moore C, Chatfield M, Richardson DP, Ashby P, Kuznesof SA, Jebb SA, Seal CJ.

School of Agriculture, Human Nutrition Research Centre, Food & Rural Development, Newcastle University, Newcastle upon Tyne NE1 7RU, UK.

Recommendations for whole-grain (WG) intake are based on observational studies showing that higher WG consumption is associated with reduced CVD risk. No large-scale, randomised, controlled dietary intervention studies have investigated the effects on CVD risk markers of substituting WG in place of refined grains in the diets of non-WG consumers. A total of 316 participants (aged 18-65 years; BMI>25 kg/m2) consuming < 30 g WG/d were randomly assigned to three groups: control (no dietary change), intervention 1 (60 g WG/d for 16 weeks) and intervention 2 (60 g WG/d for 8 weeks followed by 120 g WG/d for 8 weeks). Markers of CVD risk, measured at 0 (baseline), 8 and 16 weeks, were: BMI, percentage body fat, waist circumference; fasting plasma lipid profile, glucose and insulin; and indicators of inflammatory, coagulation, and endothelial function. Differences between study groups were compared using a random intercepts model with time and WG intake as factors. Although reported WG intake was significantly increased among intervention groups, and demonstrated good participant compliance, there were no significant differences in any markers of CVD risk between groups. A period of 4 months may be insufficient to change the lifelong disease trajectory associated with CVD. The lack of impact of increasing WG consumption on CVD risk markers implies that public health messages may need to be clarified to consider the source of WG and/or other diet and lifestyle factors linked to the benefits of whole-grain consumption seen in observational studies.​

"אבל סיבים זה בריא ללב" 🤡

 

[EMZ]

לא הבנתי מלכתחילה למה חושבים שזה בריא ללב? כאילו איפה הקשר שאמור להיות? זה כמו להגיד שזה מוריד סיכוי לגלאוקומה..
מעבר להורדת הסיכון לסרטן מעי לא חושב שראיתי משהו יותר מידי רציני

 

[Mike Bikov]

זה בא מהקטע שסיבים יכולים "להוריד" את הכולסטרול וכביכול לעזור לסירקלוציה טובה יותר לדם, מה שנגמר ומתחיל בלב.

 

[EMZ]

ואיך בדיוק סיבים מורידים כולסטרול? כאילו מה עומד מאחורי זה?