ייעוץ Q 10

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יש לי את זה במולטי במינון לא רע בכלל...לא הרגשתי משהו משמעותי באימוני כח. לא ניסיתי אירובי עם זה
 
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Effects of acute and 14-day coenzyme Q10 supplementation on exercise performance in both trained and untrained individuals.

Matthew Cooke, Mike Iosia, Thomas Buford, Brian Shelmadine, Geoffrey Hudson, Chad Kerksick, Christopher Rasmussen, Mike Greenwood, Brian Leutholtz, Darryn Willoughby, and Richard Kreider

J Int Soc Sports Nutr, March 4, 2008; 5(1): 8.

ABSTRACT: BACKGROUND: To determine whether acute (single dose) and/or chronic (14-days) supplementation of CoQ10 will improve anaerobic and/or aerobic exercise performance by increasing plasma and muscle CoQ10 concentrations within trained and untrained individuals. METHODS: Twenty-two aerobically trained and nineteen untrained male and female subjects (26.1+/-7.6 yrs, 172+/-8.7 cm, 73.5+/-17 kg, and 21.2+/-7.0%) were randomized to ingest in a double-blind manner either 100 mg of a dextrose placebo (CON) or a fast-melt CoQ10 supplement (CoQ10) twice a day for 14-days. On the first day of supplementation, subjects donated fasting blood samples and a muscle biopsy. Subjects were then given 200 mg of the placebo or the CoQ10 supplement. Sixty minutes following supplement ingestion, subjects completed an isokinetic knee extension endurance test, a 30-second wingate anaerobic capacity test, and a maximal cardiopulmonary graded exercise test interspersed with 30-minutes of recovery. Additional blood samples were taken immediately following each exercise test and a second muscle biopsy sample was taken following the final exercise test. Subjects consumed twice daily (morning and night), 100mg of either supplement for a period of 14-days, and then returned to the lab to complete the same battery of tests. Data was analyzed using repeated measures ANOVA with an alpha of 0.05. RESULTS: Plasma CoQ10 levels were significantly increased following 2 weeks of CoQ10 supplementation (p<0.001); while a trend for higher muscle CoQ10 levels was observed after acute CoQ10 ingestion (p=0.098). A trend for lower serum superoxide dismutase (SOD) was observed following acute supplementation with CoQ10 (p=0.06), whereas serum malondialdehyde (MDA) tended to be significantly higher (p<0.05). Following acute ingestion of CoQ10, plasma CoQ10 levels were significantly correlated to muscle CoQ10 levels; maximal oxygen consumption; and treadmill time to exhaustion. A trend for increased time to exhaustion was observed following 2 weeks of CoQ10 supplementation (p=0.06). CONCLUSIONS: Acute supplementation with CoQ10 resulted in higher muscle CoQ10 concentration, lower serum SOD oxidative stress, and higher MDA levels during and following exercise. Chronic CoQ10 supplementation increased plasma CoQ10 concentrations and tended to increase time to exhaustion. Results indicate that acute and chronic supplementation of CoQ10 may affect acute and/or chronic responses to various types of exercise.
PMID: 18318910
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Effects of acute and 14-day coenzyme Q10 supplementation on exercise performance in both trained and untrained individuals.

Matthew Cooke, Mike Iosia, Thomas Buford, Brian Shelmadine, Geoffrey Hudson, Chad Kerksick, Christopher Rasmussen, Mike Greenwood, Brian Leutholtz, Darryn Willoughby, and Richard Kreider

J Int Soc Sports Nutr, March 4, 2008; 5(1): 8.

ABSTRACT: BACKGROUND: To determine whether acute (single dose) and/or chronic (14-days) supplementation of CoQ10 will improve anaerobic and/or aerobic exercise performance by increasing plasma and muscle CoQ10 concentrations within trained and untrained individuals. METHODS: Twenty-two aerobically trained and nineteen untrained male and female subjects (26.1+/-7.6 yrs, 172+/-8.7 cm, 73.5+/-17 kg, and 21.2+/-7.0%) were randomized to ingest in a double-blind manner either 100 mg of a dextrose placebo (CON) or a fast-melt CoQ10 supplement (CoQ10) twice a day for 14-days. On the first day of supplementation, subjects donated fasting blood samples and a muscle biopsy. Subjects were then given 200 mg of the placebo or the CoQ10 supplement. Sixty minutes following supplement ingestion, subjects completed an isokinetic knee extension endurance test, a 30-second wingate anaerobic capacity test, and a maximal cardiopulmonary graded exercise test interspersed with 30-minutes of recovery. Additional blood samples were taken immediately following each exercise test and a second muscle biopsy sample was taken following the final exercise test. Subjects consumed twice daily (morning and night), 100mg of either supplement for a period of 14-days, and then returned to the lab to complete the same battery of tests. Data was analyzed using repeated measures ANOVA with an alpha of 0.05. RESULTS: Plasma CoQ10 levels were significantly increased following 2 weeks of CoQ10 supplementation (p<0.001); while a trend for higher muscle CoQ10 levels was observed after acute CoQ10 ingestion (p=0.098). A trend for lower serum superoxide dismutase (SOD) was observed following acute supplementation with CoQ10 (p=0.06), whereas serum malondialdehyde (MDA) tended to be significantly higher (p<0.05). Following acute ingestion of CoQ10, plasma CoQ10 levels were significantly correlated to muscle CoQ10 levels; maximal oxygen consumption; and treadmill time to exhaustion. A trend for increased time to exhaustion was observed following 2 weeks of CoQ10 supplementation (p=0.06). CONCLUSIONS: Acute supplementation with CoQ10 resulted in higher muscle CoQ10 concentration, lower serum SOD oxidative stress, and higher MDA levels during and following exercise. Chronic CoQ10 supplementation increased plasma CoQ10 concentrations and tended to increase time to exhaustion. Results indicate that acute and chronic supplementation of CoQ10 may affect acute and/or chronic responses to various types of exercise.
PMID: 18318910
לחצו כדי להרחיב...


Effects of acute and 14-day coenzyme Q10 supplementation on exercise performance in both trained and untrained individuals.

Matthew Cooke, Mike Iosia, Thomas Buford, Brian Shelmadine, Geoffrey Hudson, Chad Kerksick, Christopher Rasmussen, Mike Greenwood, Brian Leutholtz, Darryn Willoughby, and Richard Kreider

J Int Soc Sports Nutr, March 4, 2008; 5(1): 8.

ABSTRACT: BACKGROUND: To determine whether acute (single dose) and/or chronic (14-days) supplementation of CoQ10 will improve anaerobic and/or aerobic exercise performance by increasing plasma and muscle CoQ10 concentrations within trained and untrained individuals. METHODS: Twenty-two aerobically trained and nineteen untrained male and female subjects (26.1+/-7.6 yrs, 172+/-8.7 cm, 73.5+/-17 kg, and 21.2+/-7.0%) were randomized to ingest in a double-blind manner either 100 mg of a dextrose placebo (CON) or a fast-melt CoQ10 supplement (CoQ10) twice a day for 14-days. On the first day of supplementation, subjects donated fasting blood samples and a muscle biopsy. Subjects were then given 200 mg of the placebo or the CoQ10 supplement. Sixty minutes following supplement ingestion, subjects completed an isokinetic knee extension endurance test, a 30-second wingate anaerobic capacity test, and a maximal cardiopulmonary graded exercise test interspersed with 30-minutes of recovery. Additional blood samples were taken immediately following each exercise test and a second muscle biopsy sample was taken following the final exercise test. Subjects consumed twice daily (morning and night), 100mg of either supplement for a period of 14-days, and then returned to the lab to complete the same battery of tests. Data was analyzed using repeated measures ANOVA with an alpha of 0.05. RESULTS: Plasma CoQ10 levels were significantly increased following 2 weeks of CoQ10 supplementation (p<0.001); while a trend for higher muscle CoQ10 levels was observed after acute CoQ10 ingestion (p=0.098). A trend for lower serum superoxide dismutase (SOD) was observed following acute supplementation with CoQ10 (p=0.06), whereas serum malondialdehyde (MDA) tended to be significantly higher (p<0.05). Following acute ingestion of CoQ10, plasma CoQ10 levels were significantly correlated to muscle CoQ10 levels; maximal oxygen consumption; and treadmill time to exhaustion. A trend for increased time to exhaustion was observed following 2 weeks of CoQ10 supplementation (p=0.06). CONCLUSIONS: Acute supplementation with CoQ10 resulted in higher muscle CoQ10 concentration, lower serum SOD oxidative stress, and higher MDA levels during and following exercise. Chronic CoQ10 supplementation increased plasma CoQ10 concentrations and tended to increase time to exhaustion. Results indicate that acute and chronic supplementation of CoQ10 may affect acute and/or chronic responses to various types of exercise.
PMID: 18318910
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Nutrition. 2009 Nov 20. [Epub ahead of print]
Clinical aspects of coenzyme Q(10): An update.

Littarru GP, Tiano L.

Department of Biochemistry, Biology and Genetics, Polytechnic University of the Marche, Ancona, Italy.

The fundamental role of coenzyme Q(10) (CoQ(10)) in mitochondrial bioenergetics and its well-acknowledged antioxidant properties constitute the basis for its clinical applications, although some of its effects may be related to a gene induction mechanism. Cardiovascular disease is still the main field of study and the latest findings confirm a role of CoQ(10) in improving endothelial function. The possible relation between CoQ(10) deficiency and statin side effects is highly debated, particularly the key issue of whether CoQ(10) supplementation counteracts statin myalgias. Furthermore, in cardiac patients, plasma CoQ(10) was found to be an independent predictor of mortality. Studies on CoQ(10) and physical exercise have confirmed its effect in improving subjective fatigue sensation and physical performance and in opposing exercise-related damage. In the field of mitochondrial myopathies, primary CoQ(10) deficiencies have been identified, involving different genes of the CoQ(10) biosynthetic pathway; some of these conditions were found to be highly responsive to CoQ(10) administration. The initial observations of CoQ(10) effects in Parkinson's and Huntington's diseases have been extended to Friedreich's ataxia, where CoQ(10) and other quinones have been tested. CoQ(10) is presently being used in a large phase III trial in Parkinson's disease. CoQ(10) has been found to improve sperm count and motility on asthenozoospermia. Moreover, for the first time CoQ(10) was found to decrease the incidence of preeclampsia in pregnancy. The ability of CoQ(10) to mitigate headache symptoms in adults was also verified in pediatric and adolescent populations
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נכתב ע"י Moshe:
מה עשיתי לך רע? על הבוקר זה מה שאתה גורם לי לחפש...



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אתה 👑
🙌

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הכי הרבה שהוא עושה זה להאיט את הזמן לתשישות...
או בעצם מה שיותר חשוב, מגביר ספירת זרע 🤡
 
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  • פותח/ת השרשור
  • #9
כנראה שלא אראה את זה לבחור שהמליץ מאחר וזה עובד עליו כפלסיבו מעולה.. :\
תודה משה, לא התאים לי לקחת כפית שמן זית עם החרא הזה עכשיו.
 
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Q10 מחזק את שרירי הלב וניתן בדרך כלל בשילוב של מולטיויטמין (זה חלק מהסלט שם) לאנשים מעל 35.
כול זה לפי דף שמספק היצרן.
 
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  • פותח/ת השרשור
  • #11
יש משהו חוץ מקפאין שכן יעזור לי בריצות אם כבר פתחתי דיון?.

והגיוני שאחרי ספרינט 100מטר אני מרגיש ששני הרגליים שלי שבורות בכמה מקומות?.
כוס אימא של כל האנשים שלא רצו חצי שנה וחוזרים לרוץ וישר יכולים 40+דק' בקלות.
 
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שימו לב! השרשור ישן: לא היו תגובות בשרשור מעל 90 יום.

ייתכן שהתוכן בשרשור כבר אינו רלוונטי ולכן עדיף לפתוח שרשור חדש.

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