תזונה ותוספים Dietary saturate/unsaturate ratio as a determinant of adiposity.

[Mike Bikov]

Med Hypotheses. 2010 Jan 18. [Epub ahead of print]
Dietary saturate/unsaturate ratio as a determinant of adiposity.

McCarty MF.

NutriGuard Research, 1051 Hermes Ave., Encinitas, CA 92024, United States.

The characteristic leanness of vegans and adherents to "Mediterranean" diet patterns may reflect the fact that the high saturate-to-unsaturate ratio of Western omnivore diets tends to impair muscle insulin sensitivity, leading to a compensatory up-regulation of insulin secretion. Since insulin signals adipocytes to take up and retain fatty acids, a high dietary saturate-to-unsaturate ratio would be expected to promote obesity. It is proposed that, at any given level of total fat intake, the dietary saturate/unsaturate ratio will correlate positively with BMI and propensity for weight gain - a readily testable prediction. The relatively low ratios of saturates to unsaturates and of essential to non-essential amino acids in plant-based diets may be primarily responsible for the low rates of obesity, diabetes, coronary disease, and "Western" cancers observed in quasi-vegan societies.​

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